Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536686 | 0.93 | HTR6 (0.61) | HTR6 | |
| SCHEMBL1136420 | 0.92 | HTR6 (0.72) | HTR6 | |
| SCHEMBL5483480 | 0.91 | HTR6 (0.69) | HTR6DRD3 | |
| SCHEMBL14444680 | 0.88 | HTR6 (0.56) | HTR6DRD3 | |
| SCHEMBL1536590 | 0.88 | HTR6 (0.81) | HTR6 | |
| SCHEMBL5479746 | 0.87 | HTR6 (0.74) | HTR6DRD3 | |
| SCHEMBL5490011 | 0.87 | HTR6 (0.55) | HTR6DRD3 | |
| SCHEMBL14521406 | 0.86 | HTR6 (0.64) | HTR6 | |
| SCHEMBL1136413 | 0.84 | HTR6 (0.70) | HTR6 | |
| SCHEMBL5480029 | 0.84 | HTR6 (0.73) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694656-B1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2007-08-29 | — | — | EP | disclosed |
| US-7202241-B2 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202241-B2 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202241-B2 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050124613-A1 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124613-A1 | Benzoxazine derivatives and uses thereof | XDH, CYP4X1, CYP2C9 | HTR6 1872/4885DRD3 1126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.