Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.40 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480075 | 1.00 | CTSS (0.40) | CTSSCTSLCTSKRENUSP30 | |
| SCHEMBL5945990 | 0.90 | CTSS (0.40) | CTSSCTSLCTSKRENPSMB5 | |
| SCHEMBL5945985 | 0.90 | CTSS (0.40) | CTSSCTSLCTSKRENPSMB5 | |
| SCHEMBL5946006 | 0.89 | CTSS (0.39) | CTSSCTSLCTSKRENUSP30 | |
| SCHEMBL5946001 | 0.89 | CTSS (0.39) | CTSSCTSLCTSKRENUSP30 | |
| SCHEMBL5461192 | 0.87 | CTSS (0.40) | CTSSCTSLCTSKRENCTSB | |
| SCHEMBL5471927 | 0.87 | CTSS (0.40) | CTSSCTSLCTSKRENCTSB | |
| SCHEMBL5461194 | 0.87 | CTSS (0.40) | CTSSCTSLCTSKRENCTSB | |
| SCHEMBL5946098 | 0.85 | CTSS (0.40) | CTSSCTSLCTSKREN | |
| SCHEMBL5946093 | 0.85 | CTSS (0.40) | CTSSCTSLCTSKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105892-A1 | Amidino compounds as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| EP-1697355-A2 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063742-A2 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105892-A1 | Amidino compounds as cysteine protease inhibitors | CTSF, CTSB, CTSS | CTSS 3/4885CTSL 9/4885CTSK 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.