Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480498 | 1.00 | SLC6A2 (0.65) | SLC6A2SLC6A4RAB9ATMPRSS2CHRM1 | |
| SCHEMBL4717685 | 1.00 | SLC6A2 (0.65) | SLC6A2SLC6A4RAB9ATMPRSS2CHRM1 | |
| Hydrochloric Acid SCHEMBL5475867 | 0.99 | SLC6A2 (0.66) | SLC6A2SLC6A4RAB9ATMPRSS2CHRM1 | |
| Hydrochloric Acid SCHEMBL5475860 | 0.99 | SLC6A2 (0.66) | SLC6A2SLC6A4RAB9ATMPRSS2CHRM1 | |
| SCHEMBL5483002 | 0.92 | SLC6A2 (0.60) | SLC6A2SLC6A4RAB9AMAPTNPC1 | |
| SCHEMBL5483667 | 0.92 | SLC6A2 (0.60) | SLC6A2SLC6A4RAB9AMAPTNPC1 | |
| SCHEMBL5483663 | 0.92 | SLC6A2 (0.60) | SLC6A2SLC6A4RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL5480848 | 0.91 | SLC6A2 (0.60) | SLC6A2SLC6A4RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL5484192 | 0.91 | SLC6A2 (0.60) | SLC6A2SLC6A4RAB9AMAPTNPC1 | |
| SCHEMBL4717815 | 0.89 | RAB9A (0.52) | SLC6A2SLC6A4RAB9ATMPRSS2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | COMT, PNMT, GLS | SLC6A2 8/4885SLC6A4 16/4885RAB9A 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.