Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473379 | 0.99 | GPR84 (0.33) | GPR84LMNASMN1; SMN2ACEMEN1 | |
| SCHEMBL5484396 | 0.74 | MEN1 (0.33) | MEN1PABPC1KMT2A | |
| SCHEMBL14023219 | 0.61 | CA1 (0.39) | GPR84ACE2FFAR1 | |
| SCHEMBL25452623 | 0.59 | GPR84 (0.37) | GPR84ACE2FFAR1MAPTALDH1A1 | |
| SCHEMBL25452695 | 0.58 | PTPN1 (0.42) | MAPTALDH1A1 | |
| SCHEMBL5329219 | 0.57 | GPR84 (0.38) | GPR84LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6444652 | 0.57 | ALDH1A1 (0.52) | GPR84ACE2FFAR1MAPTALDH1A1 | |
| Bicarbonate SCHEMBL7175377 | 0.55 | GPR84 (0.58) | GPR84ACE2FFAR1MAPTALDH1A1 | |
| Bicarbonate SCHEMBL6439327 | 0.55 | ACE2 (0.76) | GPR84ACE2FFAR1MAPTALDH1A1 | |
| Bicarbonate SCHEMBL1098227 | 0.55 | GPR84 (0.58) | GPR84ACE2FFAR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | claimed |
| EP-1798234-B1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | TIANJIN TASLY GROUP CO LTD (CN) | 2012-06-13 | — | — | EP | disclosed |
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | disclosed |