Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479130 | 0.99 | HTT (0.40) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5477428 | 0.88 | LMNA (0.48) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5474300 | 0.87 | TSHR (0.41) | HTTMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL5477311 | 0.80 | LMNA (0.50) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5475186 | 0.79 | HTT (0.47) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5475680 | 0.78 | LMNA (0.56) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL28762091 | 0.77 | MEN1 (0.43) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5477103 | 0.77 | ALDH1A1 (0.47) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5475623 | 0.77 | LMNA (0.57) | HTTMEN1KMT2ANPSR1PDE4A | |
| SCHEMBL5707141 | 0.76 | HTT (0.41) | HTTMEN1KMT2ANPSR1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | ITO MASHITO | 2007-07-19 | — | — | US | disclosed |
| EP-1718305-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | Bayer CropScience AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005079798-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | DPYD, DHFR, TYMP | HTT 1273/4885MEN1 2836/4885KMT2A 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.