SCHEMBL5481526

SCHEMBL5481526

CO[Si](OC)(OC)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
LMNA P02545 2/20 0.42
TYR P14679 1/20 0.42
KIF11 P52732 3/20 0.41
ALDH1A1 P00352 4/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
MAPK1 P28482 2/20 0.39
TDO2 P48775 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALOX15 P16050 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HDAC1 Q13547 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5419225 0.88 NR1H2 (0.31)
SCHEMBL5412350 0.86 ESR1 (0.37)
SCHEMBL18905407 0.82 NR1H2 (0.37)
SCHEMBL50828 0.82 KDM4E (0.32) ALDH1A1MAPK1CA1CA2CA9
SCHEMBL4898228 0.81 KIF11 (0.43) TSHRKIF11ALDH1A1RAB9ACA1
SCHEMBL8999137 0.81 TSHR (0.44) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL18905542 0.80 TDO2 (0.38) TSHRKIF11ALDH1A1RAB9ANPC1
SCHEMBL5420284 0.79
SCHEMBL20279586 0.79 TSHR (0.42) TSHRLMNATYRKIF11ALDH1A1
Methoxymethane SCHEMBL28023095 0.76 TSHR (0.61) TSHRLMNATYRKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN claimed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN claimed
EP-0492966-B1 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS AS (DK) 1996-08-21 EP claimed
US-5227355-A STEREOSPECIFIC CATALYST SYSTEM INTENDED FOR THE POLYMERIZATION OF OLEFINS Seppala, Jukka (FI) 1993-07-13 US claimed
EP-0492966-A2 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS A/S (DK) 1992-07-01 EP claimed
JP-4304207-A None JP disclosed
US-11822243-B2 Negative-type photosensitive resin composition, cured film, element and display device provided with cured film, and production method therefor TORAY INDUSTRIES, INC. (JP) 2023-11-21 US disclosed
CN-110095941-B Photosensitive resin composition and method for producing semiconductor element 东丽株式会社 2023-02-17 CN disclosed
CN-109804310-B Negative photosensitive resin composition, cured film, element and display device provided with cured film, and method for producing same 东丽株式会社 2022-09-30 CN disclosed
CN-114460809-A Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-05-10 CN disclosed
CN-108885399-B Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-03-15 CN disclosed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN disclosed
CN-104011596-A PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE TORAY INDUSTRIES 2014-08-27 CN disclosed
WO-2014102813-A1 HETEROGENEOUS ZIEGLER-NATTA CATALYST SYSTEM AND A PROCESS FOR OLEFIN POLYMERIZATION USING THE SAME RELIANCE INDUSTRIES LIMITED (IN) 2014-07-03 WO disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
EP-0492966-B1 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS AS (DK) 1996-08-21 EP disclosed
US-5227355-A STEREOSPECIFIC CATALYST SYSTEM INTENDED FOR THE POLYMERIZATION OF OLEFINS Seppala, Jukka (FI) 1993-07-13 US disclosed
JP-H04304207-A STEREOSPECIFIC CATALYST FOR POLYMERIZATION OF OLEFIN NESTE OY 1992-10-27 JP disclosed
EP-0492966-A2 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS A/S (DK) 1992-07-01 EP disclosed