Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338063 | 1.00 | SOS1 (0.33) | SOS1SOS2 | |
| SCHEMBL23288551 | 0.87 | — | — | |
| SCHEMBL9562288 | 0.79 | CHRNA7 (0.36) | — | |
| SCHEMBL19358804 | 0.77 | HCN1 (0.30) | — | |
| SCHEMBL25417165 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27209964 | 0.77 | CHRNA7 (0.35) | — | |
| SCHEMBL16757277 | 0.74 | MEN1 (0.39) | — | |
| SCHEMBL31208861 | 0.74 | SOS1 (0.32) | SOS1SOS2 | |
| SCHEMBL8221048 | 0.74 | GNAI3 (0.33) | SOS1SOS2 | |
| SCHEMBL5888096 | 0.72 | OPRM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037817-A1 | Acetylenic piperazines as metabotropic glutamate receptor antagonists | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037817-A1 | Acetylenic piperazines as metabotropic glutamate receptor antagonists | GRM1, GRM5, GRIN1 | SOS1 4107/4885SOS2 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.