Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052958 | 0.81 | FUCA1 (0.58) | FUCA1S1PR1S1PR5SIGMAR1GBA1 | |
| SCHEMBL2962712 | 0.81 | FUCA1 (0.58) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL1514852 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL18339637 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL30875889 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL20417932 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL19518531 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL31327374 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL17560348 | 0.78 | FUCA1 (0.55) | FUCA1S1PR1S1PR5SIGMAR1GAA | |
| SCHEMBL10409230 | 0.77 | FUCA1 (0.50) | FUCA1S1PR1S1PR5SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225492-A1 | 3,6-Diazabicyclo[3.1.1]Heptane Derivatives with Analgesic Activity | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2007-09-27 | — | — | US | disclosed |
| EP-1751164-A1 | 3,6-DIAZABICYCLOS[3.1.1]HEPTANE DERIVATIVES WITH ANALGESIC ACTIVITY | UNIVERSITA'DEGLI STUDI DI MILANO (IT) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005108402-A1 | 3,6-DIAZABICYCLOS[3.1.1]HEPTANE DERIVATIVES WITH ANALGESIC ACTIVITY | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225492-A1 | 3,6-Diazabicyclo[3.1.1]Heptane Derivatives with Analgesic Activity | OPRK1, OPRM1, OPRD1 | FUCA1 3499/4885S1PR1 1635/4885S1PR5 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.