Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 10/20 | 0.40 |
| ▸ | CSK | P41240 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540938 | 0.76 | FLT3 (0.42) | FLT3 | |
| SCHEMBL6667816 | 0.70 | FLT3 (0.42) | FLT3CSKBTKERBB4CAMK1G | |
| SCHEMBL6667818 | 0.70 | FLT3 (0.42) | FLT3CSKBTKERBB4CAMK1G | |
| SCHEMBL3540936 | 0.70 | FLT3 (0.42) | FLT3CSKBTKERBB4CAMK1G | |
| SCHEMBL3540934 | 0.70 | FLT3 (0.42) | FLT3CSKBTKERBB4CAMK1G | |
| SCHEMBL3536853 | 0.69 | FLT3 (0.71) | FLT3CSKBTKERBB4CAMK1G | |
| SCHEMBL3536852 | 0.69 | FLT3 (0.71) | FLT3CSKBTKERBB4CAMK1G | |
| SCHEMBL9767845 | 0.68 | FERMT2 (0.47) | — | |
| SCHEMBL17829598 | 0.66 | FLT3 (0.73) | FLT3 | |
| SCHEMBL3533587 | 0.64 | TUBB4A (0.39) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854509-A2 | Methods and compositions for restoring conformational stability of a protein of the p53 family | Pfizer Products Inc. (US) | 2007-11-14 | — | — | EP | claimed |