Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.76 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482118 | 1.00 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5483306 | 0.88 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5483300 | 0.88 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL29361441 | 0.86 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL7865766 | 0.86 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL7606623 | 0.86 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL3694097 | 0.86 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL678589 | 0.86 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6914240 | 0.86 | ADRB3 (0.62) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL6910797 | 0.86 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217724-B2 | Indole, indazole, and benzazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20060063762-A1 | Indole indazole and benzazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| EP-1514869-A1 | INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063762-A1 | Indole indazole and benzazole derivative | ADRB3, ADRA2C, ADRB2 | ADRB3 1/4885ADRB1 4/4885ADRB2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.