Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065275 | 0.87 | MYC (0.50) | MYCKEAP1NFE2L2BCAT2PARP1 | |
| SCHEMBL27705082 | 0.85 | KEAP1 (0.50) | MYCKEAP1NFE2L2BCAT2PLA2G2A | |
| SCHEMBL28471957 | 0.83 | MYC (0.59) | MYCKEAP1NFE2L2BCAT2PARP1 | |
| SCHEMBL5482149 | 0.81 | MYC (0.47) | MYCKEAP1NFE2L2BCAT2PLA2G2A | |
| SCHEMBL11410320 | 0.81 | NPC1 (0.47) | TSHRCYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL1004028 | 0.78 | TSHR (0.58) | BCAT2PLA2G2APLA2G10TSHRCYP3A4 | |
| SCHEMBL8516530 | 0.78 | MYC (0.50) | MYCKEAP1NFE2L2BCAT2PARP1 | |
| Hydrochloric Acid SCHEMBL15690391 | 0.76 | TSHR (0.56) | BCAT2PLA2G2APLA2G10TSHRCYP3A4 | |
| SCHEMBL15741954 | 0.76 | MYC (0.51) | MYCKEAP1NFE2L2BCAT2PARP1 | |
| SCHEMBL22265949 | 0.75 | PLA2G2A (0.49) | BCAT2PLA2G2APLA2G10TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | CHRM3, CHRM2, CHRM5 | MYC 4532/4885KEAP1 1808/4885NFE2L2 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.