Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 8/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 7/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.40 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.40 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.40 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.40 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065283 | 0.83 | MYC (0.47) | MYCBCAT2HPGDALDH1A1MAPT | |
| SCHEMBL30410838 | 0.82 | BCAT2 (0.50) | MYCBCAT2PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL5482140 | 0.81 | MYC (0.50) | MYCBCAT2ALDH1A1MAPTNPSR1 | |
| SCHEMBL370726 | 0.81 | MYC (0.45) | MYCBCAT2HPGDALDH1A1MAPT | |
| SCHEMBL28193149 | 0.80 | PLA2G2A (0.49) | BCAT2PLA2G2APLA2G10 | |
| SCHEMBL5742619 | 0.79 | MYC (0.53) | MYCBCAT2HPGDALDH1A1MAPT | |
| SCHEMBL11212389 | 0.79 | NPC1 (0.47) | HPGDALDH1A1ALOX15PPARGPPARA | |
| SCHEMBL5550889 | 0.78 | PLA2G2A (0.47) | HPGDUSP2ALDH1A1MAPTALOX15 | |
| SCHEMBL28681774 | 0.77 | PLA2G2A (0.57) | BCAT2HPGDUSP2ALDH1A1MAPT | |
| SCHEMBL1788703 | 0.77 | BCAT2 (0.59) | MYCBCAT2HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | CHRM3, CHRM2, CHRM5 | MYC 4532/4885BCAT2 1470/4885HPGD 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.