Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.58 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065409 | 0.84 | GAA (0.63) | KMT2ATSHRRAB9APDK1PDK2 | |
| SCHEMBL4065279 | 0.83 | TP53 (0.69) | KMT2ATSHRMAPK1RAB9ANPC1 | |
| SCHEMBL6570853 | 0.82 | KMT2A (0.51) | KMT2ATSHRMAPK1ALDH1A1GLA | |
| SCHEMBL3823452 | 0.82 | CNR2 (0.49) | KMT2ATSHRMAPK1RAB9APDK1 | |
| SCHEMBL530129 | 0.81 | TP53 (0.53) | KMT2ATSHRMAPK1RAB9ATRPM8 | |
| SCHEMBL10330504 | 0.80 | KMT2A (1.00) | KMT2ATSHRMAPK1RAB9ANPC1 | |
| SCHEMBL3062368 | 0.80 | GAA (0.64) | TSHRPDK1GAA | |
| SCHEMBL10520137 | 0.79 | PDK1 (0.57) | KMT2ATSHRRAB9APDK1PDK2 | |
| SCHEMBL3052391 | 0.79 | PDK1 (0.53) | TSHRRAB9APDK1PDK2PDK3 | |
| SCHEMBL4301694 | 0.78 | GAA (0.56) | KMT2ATSHRMAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | CHRM3, CHRM2, CHRM5 | KMT2A 2219/4885TSHR 149/4885MAPK1 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.