Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065279 | 0.85 | TP53 (0.69) | KMT2ATP53TSHRMAPK1LMNA | |
| SCHEMBL5482146 | 0.82 | KMT2A (0.67) | KMT2ATP53TSHRMAPK1LMNA | |
| SCHEMBL530129 | 0.82 | TP53 (0.53) | KMT2ATP53TSHRMAPK1LMNA | |
| SCHEMBL9972492 | 0.81 | TSHR (0.61) | KMT2ATP53TSHRMAPK1MEN1 | |
| SCHEMBL4301694 | 0.80 | GAA (0.56) | KMT2ATP53TSHRMAPK1LMNA | |
| SCHEMBL20366867 | 0.79 | KMT2A (0.68) | KMT2ATSHRMAPK1MEN1ALDH1A1 | |
| SCHEMBL19673867 | 0.79 | KMT2A (0.50) | KMT2ATSHRMAPK1MEN1ERCC5 | |
| SCHEMBL9716639 | 0.78 | NR4A1 (0.51) | KMT2ATP53TSHRMAPK1LMNA | |
| SCHEMBL11081307 | 0.77 | POLB (0.43) | TP53 | |
| SCHEMBL3858610 | 0.77 | PTGS2 (0.55) | KMT2ATP53TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838448-B1 | Process for the separation of a mixture of enantiomers | DSM IP ASSETS BV (NL) | 2004-04-21 | — | — | EP | disclosed |
| US-6465684-B2 | DIASTEREOMER COMPLEX OF AT LEAST THREE COMPOUNDS, AT LEAST ONE IS A RESOLVING AGENT IN OPTICALLY ACTIVE FORM, AND AT LEAST ONE IS AN ENANTIOMER IN OPTICALLY ACTIVE FORM; RAPID SEPARATION | DSM N.V. (NL) | 2002-10-15 | — | — | US | disclosed |
| US-20010051747-A1 | Process for the separation of a mixture of enantiomers | DSM N.V. | 2001-12-13 | — | — | US | disclosed |
| US-6235927-B1 | OPTICAL RESOLUTION OF ENANTIOMORPHS OF COMPLEXES | DSM N.V. (NL) | 2001-05-22 | — | — | US | disclosed |
| EP-0838448-A1 | Process for the separation of a mixture of enantiomers | DSM N.V. (NL) | 1998-04-29 | — | — | EP | disclosed |
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051747-A1 | Process for the separation of a mixture of enantiomers | EPHX2, VKORC1, ALDH1A2 | KMT2A 4602/4885TP53 4830/4885TSHR 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.