Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530129 | 0.91 | TP53 (0.53) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL4065279 | 0.84 | TP53 (0.69) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14141689 | 0.84 | MAPT (0.52) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL9001628 | 0.81 | ADRA2C (0.71) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL10456699 | 0.81 | TP53 (0.62) | GAAMAPTLMNAKMT2AS1PR1 | |
| SCHEMBL9051702 | 0.81 | NPC1 (0.57) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL6570853 | 0.80 | KMT2A (0.51) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL10330507 | 0.80 | KMT2A (0.59) | GAAMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6570752 | 0.79 | NPC1 (0.58) | GAAMAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL10964238 | 0.79 | ALDH1A1 (0.66) | GAAMAPTSMN1; SMN2NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9717247-B2 | Synergistic fungicidal active combinations | BAYER CROPSCIENCE AG (DE) | 2017-08-01 | — | — | US | disclosed |
| US-9339037-B2 | Synergistic fungicidal active combinations | BAYER CROPSCIENCE AG (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20140371066-A1 | Synergistic Fungicidal Active Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-12-18 | — | — | US | disclosed |
| US-20090018015-A1 | Synergistic Fungicidal Active Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371066-A1 | Synergistic Fungicidal Active Combinations | CYP51A1, CYP1A2, CAT | GAA 266/4885MAPT 4442/4885LMNA 4260/4885 |
| US-20090018015-A1 | Synergistic Fungicidal Active Combinations | CYP51A1, CYP1A2, CYP3A7 | GAA 346/4885MAPT 4438/4885LMNA 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.