SCHEMBL3475153

SCHEMBL3475153

CCCCCCCCCC(C(=O)N1C(=O)CC(S(=O)(=O)O)C1=O)N1C(=O)C=CC1=O

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.31
LMNA P02545 4/20 0.31
MAPT P10636 4/20 0.31
HPGD P15428 4/20 0.31
HSD17B10 Q99714 3/20 0.31
HTT P42858 2/20 0.31
TSHR P16473 1/20 0.31
PTGS1 P23219 3/20 0.31
PTGS2 P35354 3/20 0.31
MGLL Q99685 2/20 0.31
FAAH O00519 1/20 0.31
HSP90AA1 P07900 4/20 0.30
KDM4E B2RXH2 2/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
KMT2A Q03164 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463807 0.82 ALDH1A1 (0.32) ALDH1A1LMNAMAPTHPGDHSD17B10
SCHEMBL17883835 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5482178 0.77 MME (0.43) ALDH1A1LMNAMAPTHPGDHSD17B10
SCHEMBL19646439 0.74 TP53 (0.35) ALDH1A1LMNAMAPTHPGDHSD17B10
SCHEMBL6509922 0.73 PTGS1 (0.33) ALDH1A1PTGS1PTGS2MGLLFAAH
SCHEMBL7199030 0.72 MME (0.45) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL4536010 0.72 MME (0.39) ALDH1A1LMNAMAPTHSD17B10PTGS1
SCHEMBL23801584 0.71 TP53 (0.33) ALDH1A1LMNAMAPTHPGDHSD17B10
SCHEMBL26806814 0.71 TP53 (0.33) ALDH1A1LMNAMAPTHPGDHSD17B10
SCHEMBL21575560 0.71 MME (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150231635-A1 CELLOMICS SYSTEM ON-CHIP CELLOMICS CONSORTIUM (JP) 2015-08-20 US disclosed
US-20130252848-A1 CELLOMICS SYSTEM KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY (JP) 2013-09-26 US disclosed
US-20100018862-A1 CELLOMICS SYSTEM OKANO KAZUNORI 2010-01-28 US disclosed
US-20100021933-A1 CELLOMICS SYSTEMS OKANO KAZUNORI 2010-01-28 US disclosed
US-20100016568-A1 CELLOMICS SYSTEM KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY (JP) 2010-01-21 US disclosed
US-20100016569-A1 CELLOMICS SYSTEM OKANO KAZUNORI 2010-01-21 US disclosed
US-20090325215-A1 CELLOMICS SYSTEM OKANO KAZUNORI 2009-12-31 US disclosed
US-7569354-B2 Cellomics system ONCHIP CELLOMICS CONSORTIUM (JP) 2009-08-04 US disclosed
US-20090042200-A1 CELLOMICS SYSTEM OKANO KAZUNORI 2009-02-12 US disclosed
US-20090042739-A1 CELLOMICS SYSTEM OKANO KAZUNORI 2009-02-12 US disclosed
EP-1901067-A2 Cellomics system On-Chip Biotechnologies Co., Ltd. (JP) 2008-03-19 EP disclosed
US-20070059763-A1 Cellomics system ON CHIP CELLOMICS CONSORTIUM (JP) 2007-03-15 US disclosed
EP-1626278-A2 Cellomics system OnChip Cellomics Consortium (JP) 2006-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150231635-A1 CELLOMICS SYSTEM SLC3A2, STUB1, EPCAM ALDH1A1 742/4885LMNA 2792/4885MAPT 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.