Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 12/20 | 0.57 |
| ▸ | GRM5 | P41594 | 10/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891168 | 0.74 | GRM1 (0.72) | GRM1GRM5PTGS2PTGS1FLT3 | |
| SCHEMBL2892824 | 0.73 | GRM1 (1.00) | GRM1GRM5 | |
| SCHEMBL10475874 | 0.68 | GRM1 (0.35) | GRM1 | |
| SCHEMBL29150106 | 0.67 | — | — | |
| SCHEMBL29149797 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL2889357 | 0.65 | GRM1 (0.72) | GRM1GRM5PTGS2PTGS1 | |
| SCHEMBL2890478 | 0.65 | GRM1 (0.71) | GRM1GRM5PTGS2PTGS1 | |
| SCHEMBL4150760 | 0.65 | RBP4 (0.38) | — | |
| SCHEMBL19127484 | 0.65 | MIF (0.55) | FLT3CA1CA2CA5ACA9 | |
| SCHEMBL181873 | 0.64 | MAPK14 (0.62) | PTGS2PTGS1FLT3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |