SCHEMBL5482465

SCHEMBL5482465

C=CC(=O)OC(=O)c1cccc(C(=O)OC(=O)C=C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.42
TDP1 Q9NUW8 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.36
THRB P10828 1/20 0.36
F2 P00734 1/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
EGFR P00533 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
JAK1 P23458 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28477801 0.88 PBRM1 (0.47) AKT1LOXL2F2LMNAALDH1A1
SCHEMBL6762235 0.88 PARP1 (0.49) TDP1ALDH1A1KDM4EMEN1TP53
SCHEMBL17368848 0.87 TSHR (0.33) AKT1TDP1L3MBTL1THRBLMNA
SCHEMBL1053277 0.86 AKT1 (0.54) AKT1TDP1THRBF2LMNA
SCHEMBL3973451 0.84 AKT1 (0.52) AKT1TDP1THRBF2LMNA
SCHEMBL7188576 0.84 AKT1 (0.52) AKT1TDP1THRBF2LMNA
SCHEMBL7185363 0.84 AKT1 (0.52) AKT1TDP1L3MBTL1THRBF2
SCHEMBL27691748 0.84 AKT1 (0.52) AKT1TDP1THRBF2LMNA
SCHEMBL11299190 0.84 CES2 (0.56) LMNAALDH1A1MEN1MAPTHPGD
SCHEMBL8211967 0.83 ALDH5A1 (0.41) AKT1TDP1THRBF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7215491-B2 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-05-08 US disclosed
US-20050248844-A1 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2005-11-10 US disclosed
EP-1540414-A1 OPTICAL PATH SWITCHING DEVICE AND METHOD National Institute of Advanced Industrial Science and Technology (JP) 2005-06-15 EP disclosed
WO-2004027508-A1 OPTICAL PATH SWITCHING DEVICE AND METHOD NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-04-01 WO disclosed