Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053277 | 0.98 | AKT1 (0.54) | AKT1LMNAF2TSHRTHRB | |
| SCHEMBL7185363 | 0.96 | AKT1 (0.52) | AKT1LMNAF2TSHRTHRB | |
| SCHEMBL27691748 | 0.96 | AKT1 (0.52) | AKT1LMNAF2TSHRTHRB | |
| SCHEMBL7188576 | 0.96 | AKT1 (0.52) | AKT1LMNAF2TSHRTHRB | |
| Benzoic Acid SCHEMBL27849141 | 0.94 | TSHR (0.50) | AKT1LMNAF2TSHRTHRB | |
| SCHEMBL8211967 | 0.87 | ALDH5A1 (0.41) | AKT1LMNAF2TSHRTHRB | |
| SCHEMBL27610078 | 0.87 | PDCD1 (0.50) | AKT1LMNAF2ALDH1A1MAPT | |
| SCHEMBL15798253 | 0.84 | TSHR (0.48) | AKT1TSHRTP53ALDH1A1KMT2A | |
| SCHEMBL5482465 | 0.84 | AKT1 (0.42) | AKT1LMNAF2TSHRTHRB | |
| Acrylic Acid SCHEMBL8675807 | 0.83 | AKT1 (0.56) | AKT1LMNAF2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695956-B1 | CYCLIC CARBOXYLIC ACID COMPOUND AND USE THEREOF | CHUGOKU MARINE PAINTS (JP) | 2012-06-20 | — | — | EP | disclosed |
| US-7557148-B2 | Cyclic carboxylic acid compound and use thereof | CHUGOKU MARINE PAINTS, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20070105976-A1 | Cyclic carboxylic acid compound and use thereof | CHUGOKU MARINE PLANTS, LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| CN-1886360-A | Novel cycloalkenycarboxylic acid and its uses | CHUGOKU MARINE PAINTS (JP) | 2006-12-27 | — | — | CN | disclosed |
| EP-1695956-A1 | CYCLIC CARBOXYLIC ACID COMPOUND AND USE THEREOF | CHUGOKU MARINE PAINTS, LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6630079-B2 | Bis(2- pyridinethiol-1-oxide) copper salt, does not exert any adverse influence on the storage stability or antifouling effect, and the effect of the salt does not change by the coating with an acrylic resin | API CORPORATION (JP) | 2003-10-07 | — | — | US | disclosed |
| EP-1080640-B1 | COATED BIS(2-PYRIDINETHIOL-1-OXIDE)COPPER SALT | API CORP (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-20030124085-A1 | Coated bis (2-pyridinethiol-1-oxide) copper salt | API CORPORATION (JP) | 2003-07-03 | — | — | US | disclosed |
| US-6544440-B1 | Antifouling active ingredient for a coating for the bottom of a ship, which is safe during handling; rosin coated; biocides | API CORPORATION (JP) | 2003-04-08 | — | — | US | disclosed |
| EP-1227111-A1 | TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF | Yoshitomi Fine Chemicals, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-1080640-A1 | COATED BIS(2-PYRIDINETHIOL 1-OXIDE) COPPER SALT | Yoshitomi Fine Chemicals, Ltd. (JP) | 2001-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105976-A1 | Cyclic carboxylic acid compound and use thereof | PORCN, PHOSPHO1, CA1 | AKT1 2648/4885LMNA 4390/4885F2 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.