Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145153 | 0.89 | HDAC8 (0.69) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL28800606 | 0.87 | GAA (0.53) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL808428 | 0.85 | CTSD (0.52) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL712806 | 0.83 | MAPT (0.50) | HDAC8MMP3GAAMAPTKDM4E | |
| SCHEMBL466508 | 0.81 | MAPT (0.52) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL9062637 | 0.80 | HPRT1 (0.54) | HDAC8MMP3PLK1MAPTALDH1A1 | |
| SCHEMBL659571 | 0.80 | KDM4E (0.59) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL30415690 | 0.80 | KDM4E (0.59) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL27902907 | 0.80 | KDM4E (0.59) | HDAC8MMP3PLK1GAAMAPT | |
| SCHEMBL2466597 | 0.80 | MEN1 (0.65) | HDAC8MMP3PLK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679346-B1 | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-20070123617-A1 | Polyacetal resin composition | DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT | 2007-05-31 | — | — | US | disclosed |
| EP-1679346-A1 | POLYACETAL RESIN COMPOSITION | Polyplastics Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |