Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.98 |
| ▸ | MEN1 | O00255 | 5/20 | 0.98 |
| ▸ | BLM | P54132 | 5/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.98 |
| ▸ | BCHE | P06276 | 4/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.98 |
| ▸ | MAPT | P10636 | 4/20 | 0.98 |
| ▸ | RECQL | P46063 | 4/20 | 0.98 |
| ▸ | THRB | P10828 | 3/20 | 0.98 |
| ▸ | HPGD | P15428 | 3/20 | 0.98 |
| ▸ | CASP1 | P29466 | 3/20 | 0.98 |
| ▸ | CASP7 | P55210 | 3/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.98 |
| ▸ | TERT | O14746 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55279 | 0.99 | ACHE (1.00) | ACHEMEN1BLMKMT2ABCHE | |
| SCHEMBL30379131 | 0.99 | ACHE (1.00) | ACHEMEN1BLMKMT2ABCHE | |
| Iodide SCHEMBL29527724 | 0.98 | ACHE (1.00) | ACHEMEN1BLMKMT2ABCHE | |
| Iodide SCHEMBL14996 | 0.98 | ACHE (1.00) | ACHEMEN1BLMKMT2ABCHE | |
| Iodide SCHEMBL29351886 | 0.98 | ACHE (1.00) | ACHEMEN1BLMKMT2ABCHE | |
| SCHEMBL16331307 | 0.98 | ACHE (0.98) | ACHEMEN1BLMKMT2ABCHE | |
| Bromide SCHEMBL30669741 | 0.98 | ACHE (0.98) | ACHEMEN1BLMKMT2ABCHE | |
| Bromide SCHEMBL290404 | 0.98 | ACHE (0.98) | ACHEMEN1BLMKMT2ABCHE | |
| Water SCHEMBL9106337 | 0.97 | ACHE (0.98) | ACHEMEN1BLMKMT2ABCHE | |
| SCHEMBL405355 | 0.95 | ACHE (0.92) | ACHEMEN1BLMKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114903046-A | Bactericidal composition and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-112825859-A | Bactericidal composition and application thereof | 沈阳中化农药化工研发有限公司 | 2021-05-25 | — | — | CN | claimed |
| WO-2004092739-A1 | METHOD FOR MASS SPECTROMETRY INVOLVING FLUORESCENT LABELING OF THE ANALYTE | AMERSHAM BIOSCIENCES K.K. (JP) | 2004-10-28 | — | — | WO | claimed |
| CN-117461558-B | Method for inducing diverse population of canna and identification | 中国热带农业科学院热带作物品种资源研究所 | 2024-07-12 | — | — | CN | disclosed |
| CN-117461558-A | Method for inducing diverse population of canna and identification | 中国热带农业科学院热带作物品种资源研究所 | 2024-01-30 | — | — | CN | disclosed |
| CN-116634871-A | Pesticidal compounds and compositions, methods of use and methods of preparation thereof | 阿达玛马克西姆有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-112955010-B | Microcapsule composition, method for producing same, pesticide preparation containing microcapsule composition, and method for controlling weeds | 组合化学工业株式会社 | 2022-07-26 | — | — | CN | disclosed |
| CN-110520206-B | Microfluidic filter device | 海世欧申有限责任公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-110461159-B | Fungicidal compositions | 先正达参股股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113979962-A | Fungicidal compositions | 先正达参股股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111050559-B | Pesticidally active pyrazole derivatives | 先正达参股股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| EP-1767617-A1 | Mesenchymal stem cells isolation and expansion method and uses thereof | Mazzini, Letizia (IT) | 2007-03-28 | — | — | EP | disclosed |
| EP-1003482-B1 | MICROPARTICLES FOR CONTROLLED DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | ISI IST SIEROVACCINOGENO ITAL (IT) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004092739-A1 | METHOD FOR MASS SPECTROMETRY INVOLVING FLUORESCENT LABELING OF THE ANALYTE | AMERSHAM BIOSCIENCES K.K. (JP) | 2004-10-28 | — | — | WO | disclosed |
| EP-0938675-B1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM PLC (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-6294667-B1 | SEPARATION OF THE FLUORESCENTLY LABELLED CARBOHYDRATE SUBSTANCES, BY VIRTUE OF THEIR DIFFERENT CHARGE-TO-MASS RATIOS OR OTHER FACTORS, ENABLING A LARGER NUMBER OF DIFFERENT LABELLED CARBOHYDRATE SUBSTANCES TO BE SEPARATED | AMERSHAM INTERNATIONAL PLC | 2001-09-25 | — | — | US | disclosed |
| EP-1003482-A1 | MICROPARTICLES FOR CONTROLLED DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | ISTITUTO SIEROVACCINOGENO ITALIANO I.S.I. S.p.A. (IT) | 2000-05-31 | — | — | EP | disclosed |
| EP-0938675-A1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM INTERNATIONAL plc (GB) | 1999-09-01 | — | — | EP | disclosed |
| WO-1999002135-A1 | MICROPARTICLES FOR CONTROLLED DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | ISTITUTO SIEROVACCINOGENO ITALIANO I.S.I. S.P.A. (IT) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998015829-A1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM INTERNATIONAL PLC (GB) | 1998-04-16 | — | — | WO | disclosed |