Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609506 | 0.79 | TAAR1 (0.46) | TAAR1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL5486729 | 0.78 | ALDH1A1 (0.43) | TAAR1ALDH1A1IDO1LMNA | |
| SCHEMBL9860948 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL149686 | 0.74 | GABRA1 (0.41) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL7322742 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL30267045 | 0.74 | GABRA1 (0.41) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL608459 | 0.72 | TAAR1 (0.45) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL147988 | 0.72 | PDCD1 (0.53) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL31142838 | 0.72 | TAAR1 (0.45) | GABRA1GABRB2TAAR1ALDH1A1TSHR | |
| SCHEMBL21928918 | 0.72 | GABRA1 (0.39) | GABRA1GABRB2TAAR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |