Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482813 | 0.79 | GABRA1 (0.35) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL5486703 | 0.73 | IDO1 (0.52) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL7942042 | 0.73 | ALDH1A1 (0.39) | IDO1TSHRKMT2AALDH1A1 | |
| SCHEMBL4315302 | 0.73 | TAAR1 (0.48) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL5490805 | 0.73 | PYCR1 (0.40) | TSHRPYCR1ALDH1A1L3MBTL1 | |
| SCHEMBL322857 | 0.72 | — | — | |
| SCHEMBL5081674 | 0.71 | TAAR1 (0.46) | TAAR1IDO1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1066724 | 0.71 | TAAR1 (0.46) | TAAR1TSHRLMNACYP2A13KMT2A | |
| SCHEMBL8703610 | 0.71 | TAAR1 (0.64) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL29930048 | 0.71 | TAAR1 (0.64) | TAAR1IDO1TSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |