SCHEMBL548282

SCHEMBL548282

O=C1C=C(C2CCC(C3=CC(=O)NC3=O)CC2)C(=O)N1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
DAO P14920 1/20 0.31
YTHDF3 Q7Z739 1/20 0.30
YTHDF1 Q9BYJ9 1/20 0.30
YTHDF2 Q9Y5A9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8563214 1.00 MAOA (0.34) MAOAMAOBDAOYTHDF3YTHDF1
SCHEMBL27630042 0.91 MAOA (0.45) MAOAMAOBDAO
SCHEMBL5202489 0.91 MAOA (0.41) MAOAMAOBDAO
SCHEMBL9359727 0.90 ESR2 (0.33)
SCHEMBL21496202 0.90 ESR2 (0.34)
SCHEMBL9250741 0.89 MAOA (0.44) MAOAMAOBDAO
SCHEMBL28720 0.89 MAOA (0.44) MAOAMAOBDAO
SCHEMBL8885354 0.89 MAOA (0.44) MAOAMAOBDAO
SCHEMBL28123322 0.89 MAOA (0.44) MAOAMAOBDAO
SCHEMBL10336679 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0191706-B1 THERMALLY CURABLE COMPOSITIONS BASED ON PREPOLYMERS CONTAINING STORAGE-STABLE IMIDE GROUPS, AND PROCESS FOR THEIR PREPARATION RHONE-POULENC CHIMIE (FR) 1988-08-24 EP claimed
EP-0191706-A1 Thermally curable compositions based on prepolymers containing storage-stable imide groups, and process for their preparation RHONE-POULENC CHIMIE (FR) 1986-08-20 EP claimed
US-8112028-B2 Conductive roll, cleaning roll, cleaning unit, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-20080253816-A1 CONDUCTIVE ROLL, CLEANING ROLL, CLEANING UNIT, PROCESS CARTRIDGE, AND IMAGE-FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-16 US disclosed
US-5994465-A ISOBUTYLENE-ISOPRENE COPOLYMER RUBBER. DAIKYO GOMU SEIKO, LTD. (JP) 1999-11-30 US disclosed
EP-0474406-A2 A rubber composition and a rubber article for pharmaceuticals and medical treatment DAIKYO GOMU SEIKO LTD. (JP) 1992-03-11 EP disclosed
EP-0191706-B1 THERMALLY CURABLE COMPOSITIONS BASED ON PREPOLYMERS CONTAINING STORAGE-STABLE IMIDE GROUPS, AND PROCESS FOR THEIR PREPARATION RHONE-POULENC CHIMIE (FR) 1988-08-24 EP disclosed
EP-0191706-A1 Thermally curable compositions based on prepolymers containing storage-stable imide groups, and process for their preparation RHONE-POULENC CHIMIE (FR) 1986-08-20 EP disclosed
US-4296219-A Bismide-ether compounds, compositions thereof, and method of producing same HITACHI, LTD. (JP) 1981-10-20 US disclosed
EP-0001734-B1 IMIDE GROUPS CONTAINING POLYMERS, PROCESSES FOR THEIR PREPARATION AND THEIR USES FOR MAKING VARIOUS OBJECTS RHONE-POULENC INDUSTRIES (FR) 1981-06-17 EP disclosed
EP-0004592-A1 Bisimide-ether compounds, compositions containing these compounds, and a method for their production Hitachi, Ltd. (JP) 1979-10-17 EP disclosed