Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.30 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.30 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548282 | 1.00 | MAOA (0.34) | MAOAMAOBDAOYTHDF3YTHDF1 | |
| SCHEMBL27630042 | 0.91 | MAOA (0.45) | MAOAMAOBDAO | |
| SCHEMBL5202489 | 0.91 | MAOA (0.41) | MAOAMAOBDAO | |
| SCHEMBL9359727 | 0.90 | ESR2 (0.33) | — | |
| SCHEMBL21496202 | 0.90 | ESR2 (0.34) | — | |
| SCHEMBL9250741 | 0.89 | MAOA (0.44) | MAOAMAOBDAO | |
| SCHEMBL28720 | 0.89 | MAOA (0.44) | MAOAMAOBDAO | |
| SCHEMBL8885354 | 0.89 | MAOA (0.44) | MAOAMAOBDAO | |
| SCHEMBL28123322 | 0.89 | MAOA (0.44) | MAOAMAOBDAO | |
| SCHEMBL10336679 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | claimed |
| CN-110724154-B | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | disclosed |
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | disclosed |
| CN-107043387-B | 3a, 6a- pyrrolin simultaneously [3,4-d] isoxazole -4,6- cyclohexadione compounds and its synthetic method | 上海大学 | 2019-04-02 | — | — | CN | disclosed |
| CN-105384865-B | Optical resin material, the manufacturing method of the optical resin material, the optical resin component containing the material and the polarizing film containing the component | 小池康博 | 2019-02-19 | — | — | CN | disclosed |
| CN-108627979-A | Head-mounted display component | 旭化成株式会社 | 2018-10-09 | — | — | CN | disclosed |
| CN-107230613-A | The manufacture method of separating layer formation composition, lamilate and lamilate | 东京应化工业株式会社 | 2017-10-03 | — | — | CN | disclosed |
| CN-107043387-A | 3a, 6a pyrrolin simultaneously [cyclohexadione compounds of 3,4 d] isoxazoles 4,6 and its synthetic method | 上海大学 | 2017-08-15 | — | — | CN | disclosed |
| EP-0871630-A1 | 4a,5a,8a,8b-TETRAHYDRO-6H-PYRROLO 3,4':4,5]FURO(3,2-b)PYRIDINE-6,8 7H]-DIONE DERIVATIVES FOR USE IN CONTROLLING ENDOPARASITES AND A METHOD OF PRODUCING SAID DERIVATIVES | BAYER AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997014695-A1 | 4a,5a,8a,8b-TETRAHYDRO-6H-PYRROLO[3,4':4,5]FURO(3,2-b)PYRIDINE-6,8[7H]-DIONE DERIVATIVES FOR USE IN CONTROLLING ENDOPARASITES AND A METHOD OF PRODUCING SAID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-24 | — | — | WO | disclosed |