Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27268114 | 0.80 | LMNA (0.50) | KDM4EALDH1A1MAPTHTTGRM1 | |
| SCHEMBL6262600 | 0.79 | KDM4E (0.44) | KDM4EPLD1ALDH1A1HSD17B10MAPT | |
| SCHEMBL20336407 | 0.77 | ALDH1A1 (0.42) | KDM4EPLD1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11361290 | 0.77 | KDM4E (0.38) | KDM4EGRM5 | |
| SCHEMBL4555915 | 0.76 | PLD1 (0.41) | KDM4EPLD1ALDH1A1HSD17B10MAPT | |
| SCHEMBL29782177 | 0.76 | CHI3L1 (0.54) | KDM4EPLD1ALDH1A1HSD17B10 | |
| SCHEMBL16238706 | 0.75 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HSD17B10HTTGRM1 | |
| SCHEMBL30745929 | 0.75 | HDAC6 (0.49) | KDM4EALDH1A1HSD17B10MAPTHTT | |
| SCHEMBL4919602 | 0.75 | ALDH1A1 (0.43) | KDM4EPLD1ALDH1A1HSD17B10MAPT | |
| SCHEMBL14360624 | 0.75 | HRH3 (0.50) | KDM4EALDH1A1MAPTHTTGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109324-A2 | POTENT AND SELECTIVE NAV 1.7 SODIUM CHANNEL BLOCKERS | XENON PHARMACEUTICALS, INC. (CA) | 2007-09-27 | — | — | WO | disclosed |
| US-5939553-A | Process for preparing pyridine-2,6-diamines | AKZO NOBEL N.V. (NL) | 1999-08-17 | — | — | US | disclosed |
| EP-0825985-B1 | A PROCESS FOR PREPARING PYRIDINE-2,6-DIAMINES | AKZO NOBEL NV (NL) | 1999-05-26 | — | — | EP | disclosed |
| EP-0825985-A1 | A PROCESS FOR PREPARING PYRIDINE-2,6-DIAMINES | Akzo Nobel N.V. (NL) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036607-A1 | A PROCESS FOR PREPARING PYRIDINE-2,6-DIAMINES | AKZO NOBEL N.V. (NL) | 1996-11-21 | — | — | WO | disclosed |