Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.34 |
| ▸ | TUBB | P07437 | 6/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635311 | 0.86 | PTGDR2 (0.34) | KMT2APTGDR2LMNAGAATUBB4A | |
| SCHEMBL19635324 | 0.85 | PTGDR2 (0.38) | PTGDR2LMNAGAACYP11B1CYP11B2 | |
| SCHEMBL5485146 | 0.85 | MEN1 (0.37) | KMT2APTGDR2MAPTCYP11B1CYP11B2 | |
| SCHEMBL5480913 | 0.84 | MAP3K14 (0.33) | KMT2APTGDR2TUBB4ATUBBTUBA3C | |
| SCHEMBL5480911 | 0.84 | MAP3K14 (0.33) | KMT2APTGDR2TUBB4ATUBBTUBA3C | |
| SCHEMBL5480832 | 0.84 | LMNA (0.48) | PTGDR2LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL29602500 | 0.81 | ALDH1A1 (0.39) | KMT2ALMNAMAPTHTT | |
| SCHEMBL19615288 | 0.81 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL12822022 | 0.79 | ACHE (0.40) | KMT2APIN1MAPTMAP3K14PGR | |
| SCHEMBL15698062 | 0.79 | ACHE (0.40) | KMT2APIN1MAPTMAP3K14PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185323-A1 | Method of preparing benzazepines and derivatives thereof | ECOLE POLYTECHNIQUE (FR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185323-A1 | Method of preparing benzazepines and derivatives thereof | CYP2F1, MAOB, CYP1A2 | KMT2A 788/4885PTGDR2 220/4885LMNA 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.