Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Linoleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.93 |
| ▸ | PPARD | Q03181 | 6/20 | 0.93 |
| ▸ | PPARA | Q07869 | 6/20 | 0.93 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.93 |
| ▸ | F7 | P08709 | 5/20 | 0.93 |
| ▸ | F3 | P13726 | 5/20 | 0.93 |
| ▸ | FABP4 | P15090 | 4/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.93 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.93 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.93 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.93 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.93 |
| ▸ | HPGD | P15428 | 2/20 | 0.93 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.93 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.93 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linoleic Acid SCHEMBL27343411 | 1.00 | PPARG (0.93) | PPARGPPARDPPARAALDH1A1F7 | |
| Linoleic Acid SCHEMBL28754753 | 1.00 | PPARG (0.93) | PPARGPPARDPPARAALDH1A1F7 | |
| Gamolenic Acid SCHEMBL27823852 | 0.98 | PPARG (0.93) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL21411004 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| Arachidic Acid SCHEMBL20528087 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| Linoleic Acid SCHEMBL25294178 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| Dihomo-Gamma-Linolenic Acid SCHEMBL20656585 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL22498256 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL22498258 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL18605771 | 0.96 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402389-A | Preparation method of high-strength polyphenylene sulfide film | 成都苯环新材料科技有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117402389-A | Preparation method of high-strength polyphenylene sulfide film | 成都苯环新材料科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116496351-A | Preparation method and application of antioxidant and muscle endurance improving peptide of Syringa schneid | 中国科学院南海海洋研究所 | 2023-07-28 | — | — | CN | disclosed |
| CN-110638852-B | Pure natural plant antioxidant derived from natural stevia rebaudiana and preparation method thereof | 上海维丘康敬生物科技有限公司 | 2022-05-17 | — | — | CN | disclosed |
| US-10988595-B2 | Urethane decomposing method and urethane decomposing agent | OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE (JP) | 2021-04-27 | — | — | US | disclosed |
| CN-107148410-B | Cationic lipids for nucleic acid delivery | 日油株式会社 | 2020-04-28 | — | — | CN | disclosed |
| CN-108480616-B | Powder preparation method capable of effectively controlling surface roughness of metal powder particles | 苏州思美特表面材料科技有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-110638852-A | Pure natural plant antioxidant derived from natural stevia rebaudiana and preparation method thereof | 上海维丘康敬生物科技有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110256528-A | One kind capableing of the natural oligopeptides of significant Scavenger of ROS (ROS) | 浙江海洋大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-105168339-B | A kind of preparation method and applications of dracocephalum heterophyllum total polyphenols | 中国科学院西北高原生物研究所 | 2019-09-10 | — | — | CN | disclosed |
| CN-101522033-B | Disinfectant systems and methods | SOLUTIONS BIOMED LLC | 2013-11-06 | — | — | CN | disclosed |
| CN-101522033-A | Disinfectant systems and methods | SOLUTIONS BIOMED LLC (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101516321-A | Aqueous sanitizers, disinfectants and/or disinfectants with low peroxygen content | SOLUTIONS BIOMED LLC (US) | 2009-08-26 | — | — | CN | disclosed |
| CN-101210877-A | Method for quantitative determination for crop seeds lipoxidase activity | CHENGDU RES INST OF BIOLOGY CH (CN) | 2008-07-02 | — | — | CN | disclosed |
| EP-1660653-A4 | BIODEGRADABLE POLYMER-LIGAND CONJUGATES AND THEIR USES IN ISOLATION OF CELLULAR SUBPOPULATIONS AND IN CRYOPRESERVATION, CULTURE AND TRANSPLANTATION OF CELLS | UNIV NORTH CAROLINA (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1660653-A2 | BIODEGRADABLE POLYMER-LIGAND CONJUGATES AND THEIR USES IN ISOLATION OF CELLULAR SUBPOPULATIONS AND IN CRYOPRESERVATION, CULTURE AND TRANSPLANTATION OF CELLS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20060057187-A1 | Emulsions containing unsaturated fatty acids and esters thereof | COGNIS IP MANAGEMENT GMBH (DE) | 2006-03-16 | — | — | US | disclosed |
| WO-2005021730-A2 | BIODEGRADABLE POLYMER-LIGAND CONJUGATES AND THEIR USES IN ISOLATION OF CELLULAR SUBPOPULATIONS AND IN CRYOPRESERVATION, CULTURE AND TRANSPLANTATION OF CELLS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-03-10 | — | — | WO | disclosed |
| CN-1535675-A | Cosmetic omposition containing polymer granules dispersion and plasticizing polymer compound | 莱雅公司 | 2004-10-13 | — | — | CN | disclosed |
| US-5122469-A | Using culture medium containing high levels of selected amino acids | GENENTECH, INC. (US) | 1992-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060057187-A1 | Emulsions containing unsaturated fatty acids and esters thereof | LIPC, PNLIP, ELOVL1 | PPARG 78/4885PPARD 136/4885PPARA 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.