Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ICMT | O60725 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786042 | 0.85 | HTR1A (0.64) | PKMSMN1; SMN2HTR1AMAPTKMT2A | |
| SCHEMBL6600034 | 0.84 | PKM (0.67) | PKMSMN1; SMN2HTR1AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8806727 | 0.84 | HTR1A (0.62) | PKMHTR1AMAPTKMT2AHTR1D | |
| SCHEMBL21808846 | 0.84 | PKM (0.70) | PKMSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL5177499 | 0.83 | PKM (0.68) | PKMSMN1; SMN2HTR1AALDH1A1MAPT | |
| SCHEMBL6220526 | 0.82 | PKM (0.67) | PKMGABRA1GABRB2SMN1; SMN2HTR1A | |
| SCHEMBL30419995 | 0.82 | PKM (0.67) | PKMGABRA1GABRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21808836 | 0.82 | PKM (0.67) | PKMSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL3703101 | 0.82 | PKM (0.67) | PKMGABRA1GABRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5189543 | 0.82 | PKM (0.67) | PKMSMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075931-A2 | REACTIVE HETEROCYCLIC DERIVATIVES AND METHODS FOR THEIR SYNTHESIS AND USE | BIOSITE INCORPORATED (US) | 2007-07-05 | — | — | WO | disclosed |