Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.73 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.70 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NAMPT | P43490 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763664 | 1.00 | EPHX2 (0.73) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL17822214 | 0.98 | EPHX2 (0.75) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL9809561 | 0.95 | RAB9A (0.76) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL16323089 | 0.94 | THRB (0.67) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL16341081 | 0.94 | THRB (0.67) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL25330125 | 0.92 | NAAA (0.68) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL22000501 | 0.92 | RAB9A (0.65) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL22170882 | 0.92 | EPHX2 (0.64) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL11083072 | 0.92 | NAAA (0.68) | EPHX2KEAP1NFE2L2THRBRAB9A | |
| SCHEMBL9763677 | 0.92 | NAAA (0.68) | EPHX2KEAP1NFE2L2THRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070020239-A1 | HEXIMI as a suppressor of HIV replication and cardiac hypertrophy | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-01-25 | — | — | US | claimed |
| US-7132454-B2 | HEXIM1 as a suppressor of HIV replication and cardiac hypertrophy | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-11-07 | — | — | US | claimed |
| US-7132454-B2 | HEXIM1 as a suppressor of HIV replication and cardiac hypertrophy | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-11-07 | — | — | US | disclosed |
| EP-1164413-B1 | High contrast photographic element containing a nucleator | EASTMAN KODAK CO (US) | 2006-11-02 | — | — | EP | disclosed |
| EP-1229383-B1 | High contrast photographic element containing a novel combination of nucleators | EASTMAN KODAK CO (US) | 2004-04-07 | — | — | EP | disclosed |
| US-6573021-B2 | Graphic arts | EASTMAN KODAK COMPANY | 2003-06-03 | — | — | US | disclosed |
| US-20020192589-A1 | High contrast photographic element containing a novel combination of nucleators | EASTMAN KODAK COMPANY | 2002-12-19 | — | — | US | disclosed |
| EP-1229383-A1 | High contrast photographic element containing a novel combination of nucleators | EASTMAN KODAK COMPANY (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1164413-A1 | High contrast photographic element containing a nucleator | EASTMAN KODAK COMPANY (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6245480-B1 | SUPORT COATED WITH A SILVER HALIDE EMULSION LAYER WHICH CONTAINS IN THE EMULSION LAYER OR A HYDROPHILIC COLLOID LAYER A NUCLEATING AGENT HAVING TWO LINKED NICOTINAMIDE MOIETIES AND A HYDRAZIDE MOIETY LINKED TO ONLY ONE OF THEM | EASTMAN KODAK COMPANY | 2001-06-12 | — | — | US | disclosed |