Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931166 | 0.80 | ALDH1A1 (0.40) | CYP3A4ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29406928 | 0.77 | AHR (0.46) | CYP3A4ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL1717549 | 0.77 | AHR (0.46) | CYP3A4ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL2197132 | 0.76 | CYP3A4 (0.43) | CYP3A4RAPGEF4ALDH1A1APOBEC3GMAPT | |
| SCHEMBL5490961 | 0.74 | ALDH1A1 (0.37) | ALDH1A1NPC1RAB9A | |
| SCHEMBL13609503 | 0.74 | HDAC1 (0.37) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL17921311 | 0.73 | CYP3A4 (0.41) | CYP3A4RAPGEF4ALDH1A1APOBEC3GMAPT | |
| SCHEMBL5485442 | 0.72 | — | — | |
| SCHEMBL8772397 | 0.71 | CYP3A4 (0.48) | CYP3A4RAPGEF4ALDH1A1CD44MAPT | |
| SCHEMBL28802606 | 0.71 | CYP3A4 (0.39) | CYP3A4RAPGEF4ALDH1A1APOBEC3GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |