Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931166 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5483431 | 0.74 | CYP3A4 (0.48) | ALDH1A1NPC1RAB9A | |
| SCHEMBL5482506 | 0.73 | TSHR (0.36) | TSHR | |
| SCHEMBL13609503 | 0.73 | HDAC1 (0.37) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5481495 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3166891 | 0.70 | NOTUM (0.41) | ALKBH5S1PR1 | |
| SCHEMBL189010 | 0.69 | — | — | |
| SCHEMBL30118252 | 0.69 | — | — | |
| SCHEMBL5482809 | 0.68 | HPGD (0.35) | ALDH1A1HPGDS1PR1TSHRNPC1 | |
| SCHEMBL193765 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |