Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487804 | 0.83 | GPR27 (0.54) | KAT6ARAB9AHTTNPC1ENPP3 | |
| SCHEMBL5489320 | 0.83 | GPR27 (0.60) | RAB9AHTTSMN1; SMN2NPC1ENPP3 | |
| SCHEMBL5487810 | 0.83 | GPR27 (0.54) | KAT6ARAB9AHTTNPC1ENPP3 | |
| SCHEMBL5489322 | 0.83 | GPR27 (0.60) | RAB9AHTTSMN1; SMN2NPC1ENPP3 | |
| SCHEMBL5489426 | 0.79 | IKBKB (0.60) | RAB9ASMN1; SMN2NPC1POLBMAPT | |
| SCHEMBL5489429 | 0.79 | IKBKB (0.60) | RAB9ASMN1; SMN2NPC1POLBMAPT | |
| SCHEMBL5487532 | 0.79 | KMT2A (0.62) | KAT6ARAB9AHTTSMN1; SMN2NPC1 | |
| SCHEMBL5482273 | 0.78 | GPR27 (0.48) | RAB9AHTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL6836433 | 0.76 | MAPT (0.61) | RXFP1HTTSMN1; SMN2KCNK3MAPT | |
| SCHEMBL5484229 | 0.76 | MEN1 (0.53) | RAB9AHTTNPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |