Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582539 | 0.89 | HTT (0.43) | HTTTP53ALOX12ALDH1A1LMNA | |
| SCHEMBL2887702 | 0.86 | CSNK1E (0.45) | HTTTP53ALOX12GAAPDK2 | |
| SCHEMBL2893886 | 0.86 | GPR119 (0.42) | HTTTP53ALOX12ALDH1A1LMNA | |
| SCHEMBL2894092 | 0.85 | MEN1 (0.45) | HTTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL2891520 | 0.85 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL2890817 | 0.81 | HTT (0.52) | HTTTP53ALOX12ALDH1A1LMNA | |
| SCHEMBL5481400 | 0.80 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL15988360 | 0.77 | KMT2A (0.52) | ALDH1A1P2RX7SCD5KMT2A | |
| SCHEMBL2893237 | 0.75 | HTT (0.43) | HTTTP53ALOX12ALDH1A1LMNA | |
| SCHEMBL14582401 | 0.73 | HTT (0.50) | HTTTP53ALOX12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |