Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886081 | 0.80 | KDM4E (0.32) | IDO1TDO2POLBHTT | |
| SCHEMBL16976952 | 0.58 | NPC1 (0.40) | IDO1TDO2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2891359 | 0.58 | KHK (0.49) | DCTPP1HTT | |
| SCHEMBL16976912 | 0.57 | NPC1 (0.39) | IDO1TDO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17066459 | 0.56 | ADRA2A (0.36) | — | |
| SCHEMBL16037586 | 0.55 | P2RX7 (0.40) | NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9803958 | 0.54 | ALDH1A1 (0.58) | SMN1; SMN2POLBHTT | |
| SCHEMBL544268 | 0.54 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL31144925 | 0.54 | NPC1 (0.54) | IDO1TDO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4407726 | 0.53 | ALDH1A1 (0.49) | SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |