Guaiacol

Guaiacol

SCHEMBL5483774

CCCCCCOc1ccccc1O.COc1ccccc1O.c1cnnnc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
JAK2 O60674 1/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.45
NR1I2 O75469 1/20 0.45
CHRM2 P08172 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADRA2A P08913 1/20 0.45
OPRK1 P41145 1/20 0.45
HTR2B P41595 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
ALDH1A1 P00352 2/20 0.43
CNR1 P21554 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaiacol SCHEMBL5320116 1.00 CA1 (0.49) CA1CA2TP53TSHRLMNA
Guaiacol SCHEMBL5320834 0.91 CNR1 (0.43) CA1CA2TP53TSHRLMNA
Anisole SCHEMBL27666736 0.91 MAPT (0.43) LMNAMAPTJAK2GAAMEN1
Guaiacol SCHEMBL28139981 0.88 NR5A1 (0.49) CA1CA2TP53TSHRLMNA
SCHEMBL27966447 0.86 LMNA (0.43) CA1CA2TP53TSHRLMNA
Guaiacol SCHEMBL3387344 0.86 ALOX5 (0.42) CA1CA2TP53TSHRLMNA
Guaiacol SCHEMBL480341 0.86 ALOX5 (0.42) CA1CA2TP53TSHRLMNA
SCHEMBL27957631 0.85 CNR1 (0.42) LMNAMAPTMEN1NR1I2CHRM2
Guaiacol SCHEMBL28053487 0.85 CA1 (0.42) CA1CA2TP53TSHRLMNA
SCHEMBL270163 0.84 LMNA (0.64) CA1CA2TP53TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1815844-B1 Photoprotecting compositions with reduced risk of skin sensitisation DERMATOLOGIQUES D URIAGE LAB (FR) 2015-04-29 EP claimed
EP-1815844-A2 Photoprotecting compositions reducing the risk of skin sensitisation Laboratoires Dermatologiques d'Uriage (FR) 2007-08-08 EP claimed
WO-2024120839-A1 NANOEMUSLIONS OF PLANT BASED JELLY UNILEVER IP HOLDINGS B.V. (NL) 2024-06-13 WO disclosed
EP-4243765-A1 STABLE WASH COMPOSITION Unilever IP Holdings B.V. (NL) 2023-09-20 EP disclosed
WO-2022101147-A1 STABLE WASH COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2022-05-19 WO disclosed
CN-103717073-B Comprise isosorbide monoesters and the compositions of aliphatic series vicinal diamines 克拉里安特国际有限公司 2016-06-29 CN disclosed
CN-103717071-B Comprise the composition of isobide monoesters and N-pyridone ketone CLARIANT INTERNATIONAL LTD. (CH) 2016-01-06 CN disclosed
EP-1815844-B1 Photoprotecting compositions with reduced risk of skin sensitisation DERMATOLOGIQUES D URIAGE LAB (FR) 2015-04-29 EP disclosed
CN-104010621-A Sunscreen composition with polyhydroxy quaternary ammonium salts UNILEVER NV 2014-08-27 CN disclosed
CN-102655845-B Sunscreen composition with fatty acid alkanolamides UNILEVER PLC 2014-07-23 CN disclosed
CN-103747776-A Cosmetic, dermatological or pharmaceutical composition comprising an isosorbide diester and a UV filter CLARIANT INT LTD 2014-04-23 CN disclosed
CN-102712744-A Uv absorbing complex polyester polymers, compositions containing uv absorbing complex polyester polymers, and related methods INOLEX INVESTMENT CORP 2012-10-03 CN disclosed
CN-102655846-A Sunscreen composition UNILEVER PLC 2012-09-05 CN disclosed
CN-102655845-A Sunscreen composition with fatty acid alkanolamides UNILEVER PLC 2012-09-05 CN disclosed
CN-102481246-A Sunscreen formula vanishing cream CONOPCO INC DBA UNILEVER 2012-05-30 CN disclosed
CN-102076382-A Sunscreen formula vanishing cream UNILEVER NV 2011-05-25 CN disclosed
CN-101243041-A Sunless tanning substrate PLAYTEX PRODUCTS INC (US) 2008-08-13 CN disclosed
CN-101242803-A Sunless tanning composition and method of sunless tanning PLAYTEX PRODUCTS INC (US) 2008-08-13 CN disclosed
CN-101076254-A Method and composition for reducing the appearance of wrinkles AVON PROD INC (US) 2007-11-21 CN disclosed
EP-1815844-A2 Photoprotecting compositions reducing the risk of skin sensitisation Laboratoires Dermatologiques d'Uriage (FR) 2007-08-08 EP disclosed