Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 4/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483836 | 1.00 | CYP11B2 (0.40) | CYP11B2GRIN2BVNN1SYKBTK | |
| SCHEMBL8294128 | 1.00 | CYP11B2 (0.40) | CYP11B2GRIN2BVNN1SYKBTK | |
| SCHEMBL14431020 | 0.90 | GRIN2B (0.41) | GRIN2BSYKMERTKJAK2JAK1 | |
| SCHEMBL5477801 | 0.90 | GRIN2B (0.41) | GRIN2BSYKMERTKJAK2JAK1 | |
| SCHEMBL5477796 | 0.90 | GRIN2B (0.41) | GRIN2BSYKMERTKJAK2JAK1 | |
| SCHEMBL8292579 | 0.89 | GRIN2B (0.38) | CYP11B2GRIN2BVNN1NPY5RMAPK1 | |
| SCHEMBL5481432 | 0.87 | MAP3K14 (0.34) | GRIN2BVNN1JAK2JAK3MAPK1 | |
| SCHEMBL5481427 | 0.87 | MAP3K14 (0.34) | GRIN2BVNN1JAK2JAK3MAPK1 | |
| SCHEMBL5479121 | 0.87 | KHK (0.37) | VNN1FLT3TYRO3MERTKGAS6 | |
| SCHEMBL5479125 | 0.87 | KHK (0.37) | VNN1FLT3TYRO3MERTKGAS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | claimed |
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | PKD1, PC, GPR119 | CYP11B2 27/4885GRIN2B 2653/4885VNN1 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.