SCHEMBL5483892

SCHEMBL5483892

CON=C1CC(C(=O)NCC(O)c2ccccc2)N(C(=O)c2ccc(-c3ccccc3C)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OXTR P30559 5/20 1.00
AVPR1A P37288 5/20 1.00
AVPR2 P30518 2/20 0.37
FFAR2 O15552 4/20 0.37
ROCK2 O75116 2/20 0.36
ROCK1 Q13464 2/20 0.36
LMNA P02545 1/20 0.35
PKM P14618 1/20 0.35
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP7 P09237 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4936181 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4936354 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4936543 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4940385 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4943198 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL5743780 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL5743785 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4942975 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4936174 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2
SCHEMBL4938934 1.00 OXTR (1.00) OXTRAVPR1AAVPR2FFAR2ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1725526-B1 METHOD FOR PREPARING PYRROLIDINE OXIMES SERONO LAB (CH) 2007-12-12 EP disclosed
US-20070197794-A1 Method for preparing pyrrolidine oximes APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197794-A1 Method for preparing pyrrolidine oximes PPOX, PGF, OXTR OXTR 3/4885AVPR1A 398/4885AVPR2 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.