Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484238 | 1.00 | ALDH1A1 (0.67) | ALDH1A1CES2CES1MAPTKDM4E | |
| Water SCHEMBL11590842 | 0.98 | ALDH1A1 (0.65) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL18091684 | 0.85 | ALDH1A1 (0.65) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL4382146 | 0.85 | ALDH1A1 (0.65) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL15851064 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL7645485 | 0.82 | ALDH1A1 (0.76) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL30780024 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL54610 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL28335536 | 0.80 | ALDH1A1 (0.58) | ALDH1A1CES2CES1MAPTKDM4E | |
| SCHEMBL29642587 | 0.79 | ALDH1A1 (0.67) | ALDH1A1CES2CES1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070114155-A1 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL RAFFINAGE FRANCE (FR) | 2007-05-24 | — | — | US | claimed |
| US-11753353-B2 | PBX composition | BAE SYSTEMS PLC (GB) | 2023-09-12 | — | — | US | disclosed |
| US-11753353-B2 | PBX composition | BAE SYSTEMS PLC (GB) | 2023-09-12 | — | — | US | disclosed |
| US-11746069-B2 | PBX composition | BAE SYSTEMS PLC (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746069-B2 | PBX composition | BAE SYSTEMS PLC (GB) | 2023-09-05 | — | — | US | disclosed |
| EP-3319928-B1 | PBX COMPOSITION | BAE SYSTEMS PLC (GB) | 2022-04-20 | — | — | EP | disclosed |
| US-11186528-B2 | PBX composition | BAE SYSTEMS PLC (GB) | 2021-11-30 | — | — | US | disclosed |
| US-20210317051-A1 | PBX COMPOSITION | BAE SYSTEMS PLC (GB) | 2021-10-14 | — | — | US | disclosed |
| US-20210300838-A1 | PBX COMPOSITION | BAE SYSTEMS PLC (GB) | 2021-09-30 | — | — | US | disclosed |
| US-20180215678-A1 | PBX COMPOSITION | BAE SYSTEMS PLC (GB) | 2018-08-02 | — | — | US | disclosed |
| US-20180215678-A1 | PBX COMPOSITION | BAE SYSTEMS PLC (GB) | 2018-08-02 | — | — | US | disclosed |
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-9725423-B2 | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| WO-2017006109-A1 | PBX COMPOSITION | BAE SYSTEMS PLC (GB) | 2017-01-12 | — | — | WO | disclosed |
| US-20150299146-A1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2927218-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-8535515-B2 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL FRANCE (FR) | 2013-09-17 | — | — | US | disclosed |
| US-8410145-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20070114155-A1 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL RAFFINAGE FRANCE (FR) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | ALDH1A1 78/4885CES2 1431/4885CES1 619/4885 |
| US-20150299146-A1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | RTN3, CYCS, ATL3 | ALDH1A1 3212/4885CES2 2697/4885CES1 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.