Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.47 |
| ▸ | MC5R | P33032 | 10/20 | 0.47 |
| ▸ | MC3R | P41968 | 9/20 | 0.47 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481666 | 0.92 | MC4R (0.46) | MC4RMC5RMC3RCDK4CCND1 | |
| SCHEMBL5474561 | 0.91 | MC4R (0.51) | MC4RMC5RMC3RCDK4CCND1 | |
| SCHEMBL251054 | 0.83 | HPGD (0.52) | CDK4CCND1HPGDMAPTHTT | |
| SCHEMBL207809 | 0.78 | HPGD (0.53) | HPGDMAPTHTTRECQLBCHE | |
| SCHEMBL205896 | 0.76 | HPGD (0.52) | MC4RMC5RCDK4CCND1HPGD | |
| SCHEMBL205605 | 0.75 | ACHE (0.50) | MC4RMC3RCDK4CCND1HPGD | |
| SCHEMBL208032 | 0.71 | CDK4 (0.50) | MC4RMC5RMC3RCDK4CCND1 | |
| SCHEMBL206020 | 0.70 | ACHE (0.53) | HPGDMAPTHTTRECQLBCHE | |
| SCHEMBL6275395 | 0.68 | ALDH1A1 (0.74) | HPGDMAPTHTTRECQL | |
| SCHEMBL207608 | 0.66 | BCHE (0.56) | CDK4CCND1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112007-A1 | Cyclohexyl-1, 4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112007-A1 | Cyclohexyl-1, 4-diamine compounds | PKD1, DDC, DPYD | MC4R 2380/4885MC5R 2799/4885MC3R 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.