Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.50 |
| ▸ | PPARA | Q07869 | 10/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015073 | 0.86 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5015518 | 0.86 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5017679 | 0.86 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL14010682 | 0.85 | PPARG (0.56) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL5015569 | 0.84 | PPARA (0.55) | PPARGPPARAPPARD | |
| SCHEMBL5484833 | 0.82 | SMN1; SMN2 (0.49) | PPARGPPARAPPARD | |
| SCHEMBL5488110 | 0.82 | SMN1; SMN2 (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6555933 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDGPR88 | |
| SCHEMBL6555778 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDGPR88 | |
| SCHEMBL5015605 | 0.80 | PPARG (0.65) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456293-B2 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK HOLDING CO., LTD (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456293-B2 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK HOLDING CO., LTD (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456293-B2 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK HOLDING CO., LTD (KR) | 2008-11-25 | — | — | US | disclosed |
| EP-1869004-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS, THEIR PREPARATION AND USE | SK Holdings Co., Ltd. (KR) | 2007-12-26 | — | — | EP | disclosed |
| US-20060281802-A1 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2006-12-14 | — | — | US | disclosed |
| WO-2006104349-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS, THEIR PREPARATION AND USE | SK HOLDINGS CO., LTD. (KR) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281802-A1 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SLC5A1, CPT1A, GPR119 | PPARG 166/4885PPARA 174/4885PPARD 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.