SCHEMBL5484856

SCHEMBL5484856

Oc1nnc(C(F)(F)F)[nH]1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2892232 0.80 CSNK2A1 (0.36) CSNK2A1NPSR1CSNK2A2CSNK2B
SCHEMBL12173291 0.70 CSNK2A1 (0.31) CSNK2A1NPSR1CSNK2A2CSNK2B
SCHEMBL8628938 0.68 CSNK2A1 (0.30) CSNK2A1NPSR1CSNK2A2CSNK2B
SCHEMBL12764905 0.68 L3MBTL1 (0.31) CSNK2A1NPSR1CSNK2A2CSNK2B
SCHEMBL12438043 0.65
SCHEMBL11334722 0.65
SCHEMBL11690249 0.64 L3MBTL1 (0.42)
SCHEMBL22750777 0.64
SCHEMBL13762293 0.62
SCHEMBL22750757 0.61 CTH (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232285-A1 Sulfonyl-1,2,4-triazole salts UNIVERSITE DE MONTREAL (CA) 2012-09-13 US disclosed
US-7271228-B2 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2007-09-18 US disclosed
US-20050266289-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2005-12-01 US disclosed
US-6858691-B2 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2005-02-22 US disclosed
EP-0968196-B1 PERFLUOROVINYL IONIC COMPOUNDS AND THEIR USE IN CONDUCTIVE MATERIALS ACEP INC (CA) 2004-10-27 EP disclosed
US-20040023092-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2004-02-05 US disclosed
US-6593019-B2 Ionically conducting materials, electrolytes and selective membranes ACEP INC. (CA) 2003-07-15 US disclosed
US-20020193540-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ARMAND MICHEL (CA) 2002-12-19 US disclosed
US-6426397-B1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2002-07-30 US disclosed
US-20020026021-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ARMAND MICHEL (CA) 2002-02-28 US disclosed
US-6288187-B1 CROSSLINKED ANIONIC POLYMER; ELECTROLYTES; PERMSELECTIVE MEMBRANES ACEP INC. (CA) 2001-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232285-A1 Sulfonyl-1,2,4-triazole salts STS, TST, FIS1 CSNK2A1 1747/4885NPSR1 2758/4885CSNK2A2 1832/4885
US-20020193540-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts CCNO, SCO2, CNR2 CSNK2A1 350/4885NPSR1 695/4885CSNK2A2 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.