Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330131 | 0.80 | KMT2A (0.39) | KMT2ANPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5488564 | 0.78 | IDO1 (0.56) | LMNAHTTSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2355598 | 0.78 | TAAR1 (0.40) | KMT2ANPSR1LMNAL3MBTL1MAPT | |
| SCHEMBL13932525 | 0.78 | AMY1A (0.42) | KMT2ANPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29393025 | 0.76 | KMT2A (0.48) | KMT2ANPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8230054 | 0.76 | GRIN2D (0.41) | KMT2ANPSR1LMNAL3MBTL1PTGS2 | |
| SCHEMBL7039692 | 0.76 | KMT2A (0.48) | KMT2ANPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL20083513 | 0.74 | MAPT (0.38) | KMT2ANPSR1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL12345506 | 0.74 | IDO1 (0.35) | KMT2ANPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5974477 | 0.74 | IDO1 (0.61) | KMT2ANPSR1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |