Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484887 | 0.78 | KMT2A (0.37) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL5482845 | 0.78 | HDAC3 (0.40) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL2097653 | 0.75 | IDO1 (0.65) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL11621292 | 0.75 | IDO1 (0.65) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL7614522 | 0.74 | CYP3A4 (0.43) | IDO1CYP3A4SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL283639 | 0.73 | IDO1 (0.62) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL622721 | 0.71 | IDO1 (0.60) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL1802752 | 0.71 | IDO1 (1.00) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| Hydrochloric Acid SCHEMBL21223151 | 0.71 | IDO1 (0.60) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL1047227 | 0.71 | IDO1 (0.60) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |