SCHEMBL5485000

SCHEMBL5485000

Cc1c(Br)c(Br)c(C[Si](Cl)(Cl)Cl)c(Br)c1Br

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7614541 0.84
SCHEMBL10012939 0.67 LMNA (0.31) LMNA
SCHEMBL1005276 0.67 LMNA (0.42) LMNA
SCHEMBL5487709 0.67
SCHEMBL5109742 0.67 GABRA1 (0.32) LMNA
SCHEMBL5484123 0.67
SCHEMBL5493589 0.67
SCHEMBL11389950 0.65 DRD4 (0.55)
SCHEMBL5485027 0.65
SCHEMBL95102 0.64 LMNA (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed