Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436864 | 0.87 | MKNK1 (0.47) | NPC1RAB9AMAP2K4KDM4EALDH1A1 | |
| SCHEMBL29034386 | 0.84 | DCUN1D1 (0.45) | NPC1RAB9AALDH1A1HPGDMAP4K4 | |
| SCHEMBL2819906 | 0.84 | KDM4E (0.50) | NPC1RAB9AMAP2K4KDM4EKMT2A | |
| SCHEMBL3397570 | 0.84 | DCUN1D1 (0.47) | NPC1RAB9AALDH1A1HPGDMAP4K4 | |
| SCHEMBL29499607 | 0.84 | DCUN1D1 (0.47) | NPC1RAB9AALDH1A1HPGDMAP4K4 | |
| SCHEMBL9389770 | 0.83 | MAPT (0.54) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL28489775 | 0.82 | KDM4E (0.49) | NPC1RAB9AMAP2K4KDM4EKMT2A | |
| SCHEMBL9155822 | 0.81 | ABL1 (0.47) | NPC1RAB9AKMT2A | |
| SCHEMBL7399803 | 0.78 | DCUN1D1 (0.36) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL1773521 | 0.78 | FYN (0.39) | MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072923-A1 | Process for producing 2'-(1h-tetrazol-5-yl)biphenyl-4-carbaldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-03-29 | — | — | US | claimed |
| EP-1666471-A1 | PROCESS FOR PRODUCING 2' -(1H-TETRAZOL-5-YL)-BIPHENYL-4-CARBALDEHYDE | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | claimed |
| US-20070072923-A1 | Process for producing 2'-(1h-tetrazol-5-yl)biphenyl-4-carbaldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-03-29 | — | — | US | disclosed |
| EP-1666471-A1 | PROCESS FOR PRODUCING 2' -(1H-TETRAZOL-5-YL)-BIPHENYL-4-CARBALDEHYDE | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072923-A1 | Process for producing 2'-(1h-tetrazol-5-yl)biphenyl-4-carbaldehyde | TH, CYP4B1, ABL1 | NPC1 4000/4885RAB9A 3548/4885MAP2K4 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.