SCHEMBL5485255

SCHEMBL5485255

COc1ccc(CCCCCCCCCCC[Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.53
IGF1R P08069 1/20 0.51
ALOX15 P16050 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
ALOX5 P09917 1/20 0.45
MAOB P27338 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395974 0.93 CALM1 (0.56) CALM1IGF1RALOX15TAAR1ALOX5
SCHEMBL5487907 0.85 TAAR1 (0.55) CALM1TAAR1MAOBSMN1; SMN2
SCHEMBL17400406 0.84 CALM1 (0.69) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL28218193 0.84 CALM1 (0.69) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL9509173 0.84 CALM1 (0.69) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL11007798 0.84 CALM1 (0.69) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL10571532 0.84 CALM1 (0.69) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL4254058 0.82 CALM1 (0.72) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL769798 0.80 CALM1 (0.44) CALM1IGF1RALOX15TDP1L3MBTL1
SCHEMBL1533151 0.80 CALM1 (0.55) CALM1IGF1RALOX15TAAR1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed