SCHEMBL395974

SCHEMBL395974

COc1ccc(CCC[Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.56
TAAR1 Q96RJ0 1/20 0.52
IGF1R P08069 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX5 P09917 1/20 0.47
MAOB P27338 2/20 0.47
POLB P06746 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
AOC3 Q16853 1/20 0.46
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5485255 0.93 CALM1 (0.53) CALM1TAAR1IGF1RALOX15ALOX5
SCHEMBL5487907 0.88 TAAR1 (0.55) CALM1TAAR1MAOBSMN1; SMN2SIGMAR1
SCHEMBL1533151 0.87 CALM1 (0.55) CALM1TAAR1IGF1RALOX15ALOX5
SCHEMBL17442485 0.83 MAOB (0.36) TAAR1IGF1RALOX15MAOBALDH1A1
SCHEMBL769798 0.83 CALM1 (0.44) CALM1TAAR1IGF1RALOX15MAOB
SCHEMBL1585117 0.82 CALM1 (0.58) CALM1TAAR1IGF1RALOX15ALOX5
SCHEMBL244070 0.81 CALM1 (0.79) CALM1TAAR1IGF1RALOX15ALOX5
SCHEMBL4254058 0.81 CALM1 (0.72) CALM1TAAR1IGF1RALOX15ALOX5
SCHEMBL19755183 0.81 CALM1 (0.61) CALM1TAAR1IGF1RALOX15ALOX5
SCHEMBL10577198 0.81 PTGS2 (0.46) CALM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118807829-A Modified nano catalyst for esterification reaction and preparation method and application thereof 常州大学 2024-10-22 CN claimed
CN-116285303-A High-temperature-resistant polyurethane sponge and preparation method thereof 成都达圩霞干细胞生物科技发展有限公司 2023-06-23 CN claimed
US-9182673-B2 Method for providing a template for a self-assemblable polymer for use in device lithography ASML NETHERLANDS B.V. (NL) 2015-11-10 US claimed
US-20140116980-A1 METHOD FOR PROVIDING A TEMPLATE FOR A SELF-ASSEMBLABLE POLYMER FOR USE IN DEVICE LITHOGRAPHY ASML NETHERLANDS B.V. (NL) 2014-05-01 US claimed
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US claimed
WO-2013010730-A1 METHOD FOR PROVIDING A TEMPLATE FOR A SELF-ASSEMBLABLE POLYMER FOR USE IN DEVICE LITHOGRAPHY ASML NETHERLANDS B.V. (NL) 2013-01-24 WO claimed
CN-101952195-B One-dimensional arrays of block copolymer cylinders and applications thereof MICRON TECHNOLOGY INC 2012-11-28 CN claimed
US-8101261-B2 One-dimensional arrays of block copolymer cylinders and applications thereof MICRON TECHNOLOGY, INC. (US) 2012-01-24 US claimed
CN-101952195-A The cylindrical one-dimensional array of block copolymer and its application MICRON TECHNOLOGY INC 2011-01-19 CN claimed
EP-2262721-A2 ONE-DIMENSIONAL ARRAYS OF BLOCK COPOLYMER CYLINDERS AND APPLICATIONS THEREOF Micron Technology, INC. (US) 2010-12-22 EP claimed
WO-2009102551-A2 ONE-DIMENSIONAL ARRAYS OF BLOCK COPOLYMER CYLINDERS AND APPLICATIONS THEREOF MICRON TECHNOLOGY, INC. (US) 2009-08-20 WO claimed
US-20090200646-A1 One-Dimensional Arrays of Block Copolymer Cylinders and Applications Thereof MICRON TECHNOLOGY, INC. 2009-08-13 US claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
CN-1106977-A Metallic foil with adhesion promoting layer COULD ELECTRONICS INC (US) 1995-08-16 CN claimed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP claimed
CN-118807829-A Modified nano catalyst for esterification reaction and preparation method and application thereof 常州大学 2024-10-22 CN disclosed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 CALM1 2417/4885TAAR1 222/4885IGF1R 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.