SCHEMBL548539

SCHEMBL548539

CC(=O)c1cccc(C(C)(C)O)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.53
KIF11 P52732 2/20 0.49
ALDH1A1 P00352 3/20 0.46
CES2 O00748 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309330 0.86 ACHE (0.65) ACHEKIF11ALDH1A1CES2MEN1
SCHEMBL547853 0.86 ACHE (0.55) ACHEALDH1A1CES2MEN1KMT2A
SCHEMBL2637669 0.84 RXRA (0.54) ACHEKIF11CES2
SCHEMBL29486118 0.84 RXRA (0.54) ACHEKIF11CES2
SCHEMBL27787452 0.82 PARP1 (0.55) ACHEKIF11CES2KMT2AMAPT
SCHEMBL21132592 0.82 ACHE (0.56) ACHEKIF11ALDH1A1CES2MEN1
SCHEMBL30112011 0.82 PARP1 (0.55) ACHEKIF11CES2KMT2AMAPT
SCHEMBL6559598 0.82 KIF11 (0.51) ACHEKIF11ALDH1A1CES2MEN1
SCHEMBL23412490 0.82 ACHE (0.51) ACHEKIF11ALDH1A1CES2MEN1
SCHEMBL1725123 0.82 ACHE (0.51) ACHEKIF11CES2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583904-B Treatment method and recycling method of m-diisopropylbenzene reduction mother liquor 中国石油化工股份有限公司 2024-05-28 CN claimed
CN-115583904-A Treatment method and recycling method of m-diisopropylbenzene reduction mother liquor 中国石油化工股份有限公司 2023-01-10 CN claimed
EP-0149176-B1 PROCESS FOR PRODUCING M-HYDROXYACETOPHENONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-23 EP claimed
US-4568768-A Process for producing m-hydroxyacetophenone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-04 US claimed
EP-0149176-A2 Process for producing m-hydroxyacetophenone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-24 EP claimed
EP-0111043-A1 Stabilised electrical insulating composition Licentia Patent-Verwaltungs-GmbH (DE) 1984-06-20 EP claimed
EP-0089490-A1 Insulation stabilized against high voltage Licentia Patent-Verwaltungs-GmbH (DE) 1983-09-28 EP claimed
EP-0084417-A1 Production of aromatic carbonyl compounds including novel acetophenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-27 EP claimed
JP-58118537-A None JP disclosed
JP-60132929-A None JP disclosed
JP-8310982-A None JP disclosed
JP-59029632-A None JP disclosed
US-20260049210-A1 CONTROLLED-RHEOLOGY MIXED-PLASTICS POLYPROPYLENE-BASED BLENDS BOREALIS AG (AT) 2026-02-19 US disclosed
CN-115583904-B Treatment method and recycling method of m-diisopropylbenzene reduction mother liquor 中国石油化工股份有限公司 2024-05-28 CN disclosed
US-4486605-A DECOMPOSITION OF HYDROPEROXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-04 US disclosed
JP-S5929632-A PREPARATION OF AROMATIC CARBONYL COMPOUND SUMITOMO CHEM CO LTD 1984-02-16 JP disclosed
EP-0084417-A1 Production of aromatic carbonyl compounds including novel acetophenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-27 EP disclosed
EP-0084417-A1 Production of aromatic carbonyl compounds including novel acetophenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-27 EP disclosed
JP-S58118537-A NOVEL ACETOPHENONE DERIVATIVE AND ITS PREPARATION SUMITOMO CHEM CO LTD 1983-07-14 JP disclosed
US-4273623-A ACID DECOMPOSITION OF M-DIISOPROPYLBENZENE HYDROPEROXIDE IN INERT SOLVENT IN THE PRESENCE OF AN ACID CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049210-A1 CONTROLLED-RHEOLOGY MIXED-PLASTICS POLYPROPYLENE-BASED BLENDS MFAP1, ATG13, VMP1 ACHE 3634/4885KIF11 2256/4885ALDH1A1 3231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.