Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232461 | 1.00 | PAM (0.47) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL1248561 | 1.00 | PAM (0.47) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL3402187 | 1.00 | PAM (0.47) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL17746757 | 1.00 | PAM (0.47) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL1248562 | 1.00 | PAM (0.47) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL97135 | 0.98 | PAM (0.48) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL22245646 | 0.94 | PAM (0.48) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL97322 | 0.94 | PAM (0.48) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL3795388 | 0.89 | SIGMAR1 (0.50) | PAMHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL2399949 | 0.85 | PAM (0.52) | PAMTRPA1ALDH1A1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |